News

APRIL 2019

FFC for chocolate!

 

 

#FFC #NMR #RELAXOMETRY #ANALYTICAL #INDUSTRIALAPPLICATIONS #FOOD #FOODININDUSTRY

Easter is just around the corner and we start thinking about CHOCOLATE! Indeed, FFC relaxometry can be used to study chocolate ingredients. FFC was used by University of Leeds/Nestlé to study the self-diffusion properties of cocoa butter. The advantage of FFC is evident below 1MHz where the technique shows good sensitivity to phase changes of cocoa butter.

APRIL 2019

T1 relaxation times for intracellular water from FFC measurements used as a biomarker for tumours

 

 

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Experimental evidence from the Aime group in Torino, Italy backs use of intracellular T1 at low and variable fields as a biomarker for tumours.

APRIL 2019

NMR relaxometry researcher? Need to fit your data? Try Fitteia!

 

 

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Fitteia is an open access online fitting program for NMR relaxometry data developed by expert Prof. Pedro Sebastiao from the Universidade de Lisboa, Portugal. We recommend you try this program to fit NMRD data obtained from Stelar FFC relaxometers. To use the tool, simply follow the instructions to register on the website: http://fitteia.org/

APRIL 2019

Theory backs up experimental evidence for intracellular water T1 as a tumour biomarker

 

 

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Springer and coworkers in USA have published a paper on the T1 relaxation times (R1) of intra- and extracellular water. Indeed, the difference in R1 of intracellular and extracellular water is significant and increases with decreasing magnetic field strength. This could be translated into a preclinical or clinical setting where an MRI scan at very low magnetic field could reveal tumours without the need for a contrast agent: FFC-MRI!

March 2019

H2020 Project IDentIFY: New prototype Stelar FFC NMR relaxometer

 

 

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The Stelar team successfully installed a new prototype FFC relaxometer at the CEA in Grenoble, France, as part of the Horizon 2020 project IDentIFY.

March 2018

Comprehensive book on Field Cycling NMR relaxometry available

 

 

For a good understanding of the FFC technique and some applications we recommend you read Kimmich’s most recent book, published by the Royal Society of Chemistry.

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March 2018

FFC NMR relaxometry used in the work towards the 2018 Nobel Prize for Chemistry

 

 

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Frances Arnold (CalTech) 2018 Nobel Prize in Chemistry, was cited for “the directed evolution of enzymes”, which he has demonstrated in many chemical systems or processes.

 

Her lab with that of Eric Brustad (MIT) used directed evolution to produce an enzyme for production of MRI probes of dopamine and serotonin.

 

We are proud to see that Stelar instrumentation and Fast Field Cycling NMR is one of experimental methods adopted.

 

March 2018

In memory of Seymour Koenig -
a founder of field cycling relaxometry

 

 

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We are very sorry to hear of the recent loss of a field cycling relaxometry godfather, Seymour Koenig. The Koenig-Brown field cycling relaxometer was a great motivation to Stelar Srl to develop commercial field cylcing relaxometers.

You can read more about Seymour Koenig's achievements on the ISMRM and CERM websites.

january 2018

FFC NMR applications booklet

 

 

 

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download booklet

January brings the breeze of science! and with it the new Stelar FFC NMR application booklet, in which you can find information about new FFC NMR instruments and the latest techniques regarding various application fields like MRI Contrast Agents, Therapeutic Proteins, Food, Polymers, Porous Materials and Oil Industry, Heteronuclei and new In-Vivo Applications.

You can download here our booklet

 

november 2017

Ultra-powerful Fast Field Cycling MRI scanner scans first patients

 

 

 

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Great news from our partners in Project Identify. Prof. David Lurie and coworkers have successfully scanned the first patients in the FFC MRI scanner at Aberdeen University. FFC MRI scanners have been liked to having 100 MRI scanners in just one MRI scanner. This ultra-powerful scanner is expected to be the next generation of MRI scanner adopted by hospitals to provide more detailed disease diagnoses.


Read more here and here.

february 2016

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Stelar NMR YouTube channel

 

 

 

Visit the Stelar YouTube channel "Stelar NMR" to find out more about FFC NMR relaxometry and more.

12th february 2016

Fast Field Cycling magnetic resonance technlogy developed by Stelar srl to be key part of multimillion eu-funded development of new generation of MRI scanners

 

 

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Stelar Srl is part of a consortium of nine European partners, led by the University of Aberdeen, who have received 6.6 million Euro of funding from the European Union Horizon 2020 research grant scheme for the development of next-generation MRI scanners designed to identify key diseases earlier and in more detail. The new scanners will be based on the Fast Field Cycling(FFC)-MRI method, thought to be the first of its type in the world for human studies, and will provide much more detailed information about diseases including osteoarthritis, cancer and dementia. Current standard MRI scanners work at just one fixed magnetic field, however FFC-MRI scanners will allow patients to undergo an MRI scan with thousands of possible variations in the magnetic field, giving considerably more information about tissues and organs in the body. Stelar Srl, based in Mede, Italy, has unique and world-leading expertise in the production of instrumentation for Fast Field Cycling magnetic resonance technologies, and will be a key industrial partner in the development of these new FFC-MRI scanners. Quote from Gianni Ferrante: “I am very proud that Stelar is a key partner in this EU project of high importance and value to future medical diagnostics. Stelar’s involvement in this project will aim to develop an improved version of Fast Field Cycling technology for clinical MRI. FFC-MRI involves measuring the dependency of the T1 relaxation time on the magnetic field strength which allows us to obtain a fingerprint which will vary for different disease states. This novel FFC-MRI technology will lead to the advent of a new generation of MRI scanners capable of covering continuously a wide range of magnetic field strengths which will allow, in particular, the acquisition of magnetic resonance images at very low magnetic fields where there is a wealth of untapped medical diagnostic information. I am indeed confident we will succeed in bringing this new FFC-MRI technology to the field of in vivo medical imaging technologies. The innovative FFC technology to be developed for the new generation FFC-MRI scanner during the course of this project will also mark a milestone in the development of FFC technology for the unique magnetic resonance relaxometry instrumentation manufactured and commercialized by Stelar. FFC magnetic resonance relaxometers are used for the analysis of a wide range of materials, such as MRI contrast agents for medical diagnostics, polymers for the plastics and car tyre industries, rock cores for the oil and gas industry, electrolytes for developing batteries, proteins for the pharmaceutical and biotech industries and foodstuffs for defining shelf-life and fraud in the food industry, to name a few.” Quote from project coordinator, Prof. David Lurie, University of Aberdeen: “There is a whole range of diseases where FFC-MRI could benefit diagnosis and monitor the success of treatment – early tests show it can measure changes in cartilage in osteoarthritis and our research has also shown that there are changes visible in cancer. We believe there may be changes in many other conditions too. The signals measured by FFC-MRI are a function of what’s happening on a molecular level in tissues which is where disease begins but we’re not absolutely certain what is happening, and what’s causing these changes – that is what this new project will aim to explore, as well as developing techniques to improve the scanners and to provide better quality images of the body.” The 4-year project “Improving Diagnosis by Fast Field-Cycling MRI” (code named “IDentiFY”) kicked off in January 2016 and involves seven academic and two industrial partners from six EU countries.

 

YouTube link: MRI Scanners: The next generation

 

Events

JUNE 2019

FFCRelax Conference, 5-7 June, Pisa, Italy

LINK FFC RELAX

LINK ICCOM

#FFCRELAX2019
#STELARSRL

Stelar are offering 5 fellowships covering the registration fee for scientists under 35 for the FFCRelax2019 conference, 5-7 June, Pisa, Italy. Please apply through the conference website. Deadline for applications is 15th April.

APRIL 2019

Stelar at 60th ENC, 7-12 April, Asilomar, USA

 

#ENC2019

Come and visit Stelar at Booth 1, at the ENC in Asilomar, for a cup of authentic Italian expresso coffee and find out more about FFC NMR relaxometry applications. There are some new developments regarding applications in preclinical medical diagnosis, battery materials and rock cores for the oil and gas industry.

 

Stelar is also pleased to collaborate with Quantum Design (Booth 5) for distribution of Stelar FFC relaxometers in North and South America.

MARCH 2019

COST action workshop on NMR relaxometry for interdisciplinary and industrial applications, CEA Grenoble, 19-22 March

 

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The COST workshop on NMR relaxometry for interdisciplinary and industrial applications was successful in transmitting a lot of high-quality science and how both the classical time domain relaxometry at low and high fields and Fast Field Cycling relaxometry, covering a wide range of magnetic fields, can be used as powerful complimentary techniques. Industrial participants came away with a positive impression of NMR relaxometry and new insights into the power of these techniques.

FEBRUARY 2019

COST action training school on NMR relaxometry data analysis: theory and software, University of Pavia, Italy, 19-22 February

 

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A good attendance at the COST relaxometry data analysis training school in Pavia, Italy. Understanding theories and software used to elaborate relaxometry data is a hot topic for many newcomers to NMR relaxometry. Events like this help to spread the understanding and use of NMR relaxometry, thanks to COST action 15209 EURELAX!

4-8 March 2018

Panic 2018 conference:
INFORMAL SCIENTIFIC

EVENT - MEET THE EXPERT

 

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DOWNLOAD POSTER

If you attending the PANIC conference in La Jolla (CA, USA) next week, 4-8 March 2018, remember that there is more to NMR than just spectroscopy! If you want a different take on NMR we can recommend the following fast field cycling relaxometry presentations, particularly if you are interested in polymers or battery materials:

 

Marius Hofmann, Universität Bayreuth:

“Field-Cycling NMR and its Application to Study Molecular Dynamics”

The presentation will cover polymers and the close relationship between commonly applied macroscopic rheology and FC NMR as a method of microscopic rheology;

 

Poster 39:

“NMR Fast Field Cycling relaxometry for liquid and solid electrolytes - application in the battery industry”.

D. Kruk, M. Florek-Wojciechowska, O. Tutusaus, M. Pasin, G. Ferrante, R. Steele

 

You are also invited to attend our “MEET THE FFC EXPERT” informal scientific event hosted at the STELAR STAND on TUESDAY 6TH MARCH 6.45 pm.

Independent FFC expert, Dr. Marius Hofmann will be available to answer all your questions on FFC.

16th March 2018

One-day Symposium on Fast Field-Cycling MRI

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DOWNLOAD THE PROGRAM

This one-day Symposium is being held to mark the mid-point of the “IDentIFY” EU Horizon-2020 project on FFC-MRI. Its objective is to inform stakeholders and potential beneficiaries about the current status of FFC-MRI and to indicate its future direction and potential capabilities for enhancing the diagnosis and staging of disease, as well as the monitoring of treatment. In addition, lectures will be given by the leaders of three other Horizon-2020 projects related to magnetic resonance.

Registration is free of charge! Details and registration form HERE

29TH JANUARY 2018

COST ACTION Conference on NMR Relaxometry and related methods

 

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DOWNLOAD THE PROGRAM

The COST ACTION European Network on NMR Relaxometry is doing a great job in spreading the word on the applications and benefits of using NMR relaxometry.

The conference on NMR relaxometry and related methods, taking place in Torino, Italy, (29 Jan to 01 Feb 2018) has attracted many researchers old and new

 

2-6 December 2017

ANZMAG 2017,
Kingscliff NSW,
Australia

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DOWNLOAD THE PROGRAM

Stelar is a GOLD sponsor of the ANZMAG conference this year and is also proud to sponsor a world-renowned scientist at the conference, Prof. Silvio Aime (University of Turin, Italy), with a hot topic to present: Relaxometry and cancer – including in vivo FFC.

We will also be hosting “MEET THE FFC EXPERT”, an informal scientific event at the Stelar stand in during the Monday evening poster session. The perfect opportunity to meet and ask questions to some top scientists working with FFC NMR relaxometry.

 

25-28 September 2017

39th FGMR Annual Discussion Meeting, Bayreuth, Germany

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Stelar is a sponsor of the FGMR meeting and will be holding live demos of the SMARtracer bench-top FFC relaxometer in Bayreuth.

Come and visit our booth with your own sample to run or for information on FFC instruments and applications.

Don't miss the plenary lecture by Prof. J.-P. Korb on "Applications of FFC NMR relaxometry for probing molecular dynamics of complex liquids in confinement".

5-7 June 2017

10th Conference on FFC NMR Relaxometry

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The perfect opportunity to meet FFC NMR Relaxometry experts from around the globe and find out about the latest applications of the technique and new evolutions of the technology. This special event in the calendar of FFC researchers is held every second year and the next appointment is coming very soon. Stelar is a proud spnosor of this event and will be holding a special evening presentation and round-table discussion during the conference. There is still time to register (please contact the organizers, information on the website

26 - 31 March 2017

58th Experimental Nuclear Magnetic Resonance Conference March 26 - 31, 2017 Asilomar Conference Grounds, Pacific Grove, California

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Come and visit STELAR at the 58th ENC. Find out more about the latest fascinating results of Fast Field Cycling (FFC) relaxometry applied to chemistry of MRI Contrast Agent and preclinical MRI. This year we are proud to present the first "in vivo” FFC-NMRD characterization of tumour tissues. (Poster #327) We are looking forward to meeting you in Asilomar and welcome you at booth #1 with an authentic cup of Italian espresso coffee (the real thing, not a watered-down version!).

February 2017

PANIC 2017 Conference Hilton Head Island SC- USA: Don’t PANIC, there is more to NMR than just spectroscopy!

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The PANIC 2017 conference is just a few days away and we are looking forward to meeting you in Hilton Head Island ! Come and visit STELAR at booth to find out more about applications of Fast Field Cycling (FFC) relaxometry in industrial applications. In particular, Stelar’s tailored FFC relaxometry solution for polymer industry and chemistry of MRI CA will be presented.

This year, renowned FFC expert Prof. Ernst Roessler University of Bayreuth (D) will be giving on Monday a presentation on ‘Field-Cycling NMR Relaxometry as a Versatile Tool of Molecular Rheology’.

Prof. Roessler will also be available to answer particular questions on how FFC can be applied polymer rheology.

Also showcasing in the poster sessions are applications of FFC relaxometry for MRI-Constrast Agent and preclinical MRI (poster title: "the first T1 FFC-NMRD Profile of a Tumour Bearing Mouse”) and for industrial polymers (poster title “Potential of Fast Field Cycling NMR Relaxometry to Address Issues in Polymer Melt“).

If all this isn’t enough to tempt you to pass by and have a chat with us, then come along and take advantage of the Italian sweet treats we will be offering.

September 2016

13th INTERNATIONAL BOLOGNA CONFERENCE ON MAGNETIC RESONANCE IN POROUS MEDIA

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Don’t miss Magnetic Resonance and Porous Media conference at the University of Bologna!

From 4th to 8th September STELAR staff will be there to welcome you and present a bunch of exciting news about FFC and much more! Our latest works of Fast Field Cycling NMR relaxometry applied to proteins, polymers, and rock cores will be presented.

A new bench-top FFCNMR relaxometer for large samples will be demonstrated and available for real measurements. We look forward to welcoming you at our booth and starting new challenging conversations. Don’t miss this opportunity!

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